The Influence of Risk Factors on Perioperative Results of Multivessel Coronary Artery Bypass Grafting Through the Left Anterior Minitoracotomy

  • O. D. Babliak Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
  • V. M. Demianenko Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
  • D. E. Babliak Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
  • A. I. Marchenko Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
  • E. A. Melnyk
  • K. A. Revenko Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
  • L. V. Pidgaina Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
  • O. S. Stohov Cardiosurgery Center of Dobrobut Health Care Network, Kyiv, Ukraine
Keywords: minimally invasive coronary artery bypass grafting, coronary artery disease, risk factors

Abstract

Multivessel coronary artery bypass grafting (CABG) through the left anterior minitoracotomy using the technique of total coronary revascularization via left anterior thoracotomy (TCRAT) is routinely performed in our institution since July 2017. This technique is used in all patients regardless of the number of anastomoses, quality and location of coronary targets, body mass index, age, comorbidities and predicted postoperative risk.

The aim. To present the results of 349 consecutive patients with isolated multivessel coronary artery disease who underwent minimally invasive CABG. To compare perioperative outcomes of minimally invasive CABG in patients with existent risk factors for CABG and to identify possible contraindications to the use of this CABG technique.

Materials and methods. From July 2017 to January 2020, 357 consecutive patients were underwent multivessel CABG at our institution. Eight (2.3%) patients in whom CABG was performed through the median sternotomy were excluded from the study. The remaining 349 (97.7%) patients underwent complete myocardial revascularization through the left anterior minitracotomy using TCRAT technique (peripheral cannulation for cardiopulmonary bypass (CPB), cold blood cardioplegia). All the patients were divided into groups according to the presence of risk factors (obesity, old age, diabetes, risk of postoperative mortality greater than 2.0 calculated by EuroSCORE II scale) to analyze the impact of these factors on intraoperative and postoperative parameters.

Results. Intra- and postoperative parameters in patients of all groups were within safe limits. There was no statistically significant difference between the patients older and younger than 70. Diabetic and obese patients had a longer total operation time (on average by 5%, p = 0.003 and 7%, p = 0.019, respectively), CPB time (on average by 8%, p = 0.002 and 11%, p = 0.0001, respectively) and intensive care unit stay (on average by 15%, p = 0.004 and 17%, p = 0.013, respectively) compared to the patients without these conditions. The patients with EuroSCORE II risk more than 2.0 were had longer main phase of the operation (on average by 12 minutes, i.e. 8%, p = 0.013), they required longer ventilation time (by 27%, p = 0.036), longer stay in the intensive care unit (by 23%, p = 0.0004), had a longer hospital stay (by 15%, p < 0.0001), they were more likely to have acute kidney damage that required hemodialysis, and mortality was observed only in this group of patients. However, even in this group of severe patients, the incidence of complications and mortality did not exceed the predicted rates.

Conclusions. The technique of minimally invasive CABG through the left anterior thoracotomy allow the possibility to avoid median sternotomy in 97.7% of patients with multivessel coronary artery disease.

The technique of minimally invasive multivessel CABG through the left anterior thoracotomy is universal and does not require patient selection, because it can be used effectively and safely regardless of obesity, diabetes or old age.

This technique can be performed in patients with any EuroSCORE II rate without the mortality rate increase.

References

  1. Safaei N, Alikhah H, Abadan Y. Coronary Risk Factors in Patients Underwent Coronary Artery Bypass Grafting. Pak J Biol Sci. 2011 Jan 1;14(1):25-33. https://doi.org/10.3923/pjbs.2011.25.33
  2. Gürbüz HA, Durukan AB, Salman N, Uçar Hİ, Yorgancıoğlu C. Obesity is still a risk factor in coronary artery bypass surgery. Anadolu Kardiyol Derg. 2014 Nov;14(7):631-637. https://doi.org/10.5152/akd.2014.4954
  3. Tsuneyoshi H, Komiya T, Shimamoto T, Sakai J, Hiraoka T, Wada K, Kaneko H, Fujimoto Y, Furuichi Y, Jinno T, Tominaga O. Risk Factors for Poor Prognosis of Coronary Artery Bypass Grafting in the Patients with Diabetes. J Jpn Coron Assoc. 2016;22(4):251-257. https://doi.org/10.7793/jcoron. 22.16-00014
  4. Natarajan A, Samadian S, Clark S. Coronary artery bypass surgery in elderly people. Postgrad Med J. 2007;83(977):154-158. https://doi.org/10.1136/pgmj.2006.049742
  5. Oktar G, Imren V, Erer D, Iriz E, Gokgoz L, Soncul H. Coronary artery bypass graft surgery in the elderly patients. Open Medicine. 2009;4(2):218-221. https://doi.org/10.2478/s11536-008-0077-z
  6. Shan L, Saxena A, McMahon R, Newcomb A. Coronary Artery Bypass Graft Surgery in the Elderly: a Review of Postoperative Quality of Life. Circulation. 2013;128(21):2333-2343. https://doi.org/10.1161/CIRCULATIONAHA.112.000729
  7. Nashef SA, Roques F, Sharples LD, Nilsson J, Smith C, Goldstone AR, Lockowandt U. EuroSCORE II. Eur J Cardiothorac Surg. 2012 Apr;41(4):734-744; discussion 744-745. https://doi.org/10.1093/ejcts/ezs043
  8. McGinn JT Jr, Usman S, Lapierre H, Pothula VR, Mesana TG, Ruel M. Minimally invasive coronary artery bypass grafting: dual-center experience in 450 consecutive patients. Circulation. 2009;120:S78-S84. https://doi.org/10.1161/CIRCULATIONAHA.108.840041
  9. Head SJ, Kieser TM, Falk V, Huysmans HA, Kappetein AP. Coronary artery bypass grafting: Part 1--the evolution over the first 50 years. Eur Heart J. 2013 Oct;34(37):2862-2872. https://doi.org/10.1093/eurheartj/eht330
  10. Kikuchi K, Mori M. Minimally invasive coronary artery bypass grafting: a systematic review. Asian Cardiovasc Thorac Ann. 2017 Jun;25(5):364-370. https://doi.org/10.1177/ 0218492317692465
  11. Rodriguez M, Ruel M. Minimally invasive multivessel coronary surgery and hybrid coronary revascularization: can we routinely achieve less invasive coronary surgery? Methodist Debakey Cardiovasc J. 2016 Jan-Mar;12(1):14-19. https://doi.org/10.14797/mdcj-12-1-14
  12. Nambiar P, Mittal C. Minimally invasive coronary bypass using internal thoracic arteries via a left minithoracotomy: "the Nambiar Technique". Innovations (Phila). 2013 Nov-Dec;8(6):420-426. https://doi.org/10.1097/IMI.0000000000000035
  13. Grossi EA, Groh MA, Lefrak EA, Ribakove GH, Albus RA, Galloway AC, Colvin SB. Results of a prospective multicenter study on port-access coronary bypass grafting. Ann Thorac Surg. 1999 Oct;68(4):1475-1477. https://doi.org/10.1016/s0003-4975(99)00959-5
  14. Gulielmos V, Brandt M, Knaut M, Cichon R, Wagner FM, Kappert U, Schüler S. The Dresden approach for complete multivessel revascularization. Ann Thorac Surg. 1999 Oct;68(4):1502-1505. https://doi.org/10.1016/s0003-4975(99)01032-2
  15. Dogan S, Aybek T, Andressen E, Byhahn C, Mierdl S, Westphal K, Matheis G, Moritz A, WimmerGreinecker G. Totally endoscopic coronary artery bypass grafting on cardiopulmonary bypass with robotically enhanced telemanipulation: report of forty-five cases. J Thorac Cardiovasc Surg. 2002 Jun;123(6):1125-1131. https://doi.org/10.1067/mtc.2002.121305
  16. Subramanian VA, Patel NU, Patel NC, Loulmet DF. Robotic assisted multivessel minimally invasive direct coronary artery bypass with port-access stabilization and cardiac positioning: paving the way for outpatient coronary surgery? Ann Thorac Surg. 2005 May;79(5):1590-1596. https://doi.org/10.1016/j.athoracsur.2004.10.067
  17. Babliak O, Demianenko V, Melnyk Y, Revenko K, Pidgayna L, Stohov O. Complete Coronary Revascularization via Left Anterior Thoracotomy. Innovations (Phila). 2019;14(4):330-341. https://doi.org/10.1177/1556984519849126
  18. Babliak OD, Demianenko VM, Melnyk EA, Revenko KA, Pidhayna LV, Stohov OS. [Miniinvasive multivessel coronary grafting through left anterior thoracotomy]. UMJ Heart & Vessels. 2018 May 18;(1):65-69. Ukrainian. https://doi.org/10.30978/hv2018165
  19. Babliak O, Demianenko V, Babliak D, Melnyk E, Revenko K, Stohov OS. Innovative approach – minimally invasive multivessel coronary grafting through a left anterior thoracotomy. Proceedings of the Shevchenko Scientific Society. Medical Sciences. 2019;55(1):65-76. https://doi.org/10.25040/ntsh2019.01.06
  20. WHO [Internet]. Copenhagen: WHO; c2020 [cited 12 April 2020]. Body mass index - BMI; [about 1 screen]. Available from: http://www.euro.who.int/en/health-topics/disease-prevention/nutrition/a-healthy-lifestyle/body-mass-index-bmi
Published
2021-10-27
How to Cite
Babliak, O. D., Demianenko, V. M., Babliak, D. E., Marchenko, A. I., Melnyk, E. A., Revenko, K. A., Pidgaina, L. V., & Stohov, O. S. (2021). The Influence of Risk Factors on Perioperative Results of Multivessel Coronary Artery Bypass Grafting Through the Left Anterior Minitoracotomy. Transplantation and Artificial Organs, (2 (03), 17-36. https://doi.org/10.30702/transpaorg/10_21.2710/0317-36/132.2
Section
SCIENTIFIC PUBLICATIONS